Dna

History of Biology

  • Walter Sutton and Theodor Boveri

    Walter Sutton and Theodor Boveri
    Walter Sutton observed chromosomal movement and discovered that choromosomes occur in pairs and named Mendel's functions genes (with Theodor Boveri).
  • Nettie Stevens and Edmund Wilson

    Nettie Stevens and Edmund Wilson
    Nettie Stevens and Edmund Wilson seperatley discovered differences in female (XX) and male (XY) chromosomes.
  • William Bateson and Reginald Punnett

    William Bateson and Reginald Punnett
    William Bateson coined the word genetics and showed that some genes are linked (with Reginald Punnett).
  • Archibald Garrod

    Archibald Garrod
    Archibald Garrod reported the recessive nature of the condition followed Mendel's principles and called it an inborn error of metabolism.
  • Godfrey Hardy and Wilhelm Weinberg

    Godfrey Hardy and Wilhelm Weinberg
    Godfrey Hardy and Wilhelm Weinberg established the Hardy-Weinberg theorom and found the results of cross 2 heterozygous. MM 2MN NN
  • Thomas Morgan

    Thomas Morgan
    Thomas Morgan proved that genses are carried on chromosomes. He also started using fruit flies and demonstrated the existance of sex-linked genes.
  • Alfred Sturtevant and Estella Elinor Carothers

    Alfred Sturtevant and Estella Elinor Carothers
    Alfred Sturtevant created the first gene map and Estella Elinor Carothers showed the first conclusive evidence that chrosomes are independently assorted.
  • RA Fisher, Sewell Wright, and JBS Haldane

    RA Fisher, Sewell Wright, and JBS Haldane
    RA Fisher, Sewell Wright, and JBS Haldane were pro-eugenics.
  • Herman Muller

    Herman Muller
    Herman Muller showed that fruit flies mutated more when exposed to x-rays.
  • Frederick Griffith

    Frederick Griffith
    Frederick Griffith discovered the tranformation of bacteria using virulent "S" and non-virulant "R".
  • George Beadle and Edward Tatum

    George Beadle and Edward Tatum
    George Beadle and Edward Tatum presented the one gene encodes for one enzyme/protein theory.
  • Oswald Avery

    Oswald Avery
    Oswald Avery reasoned that Griffith's transforming factor was inside the bacteria and proved that DNA carries genese and insprired Watson and Crick.
  • Oswald Avery, Colin Macleod, and Maclyn McCarty

    Oswald Avery, Colin Macleod, and Maclyn McCarty
    Oswald Avery, Colin Macleod, and Maclyn McCarty isolate DNA as genetic material.
  • Erwin Chargaff

    Erwin Chargaff
    Erwin Chargaff determined that there is always a ratio of 1:1 for adenine and thyamine. 3 years later this would determine the structure of DNA.
  • Rosalind Franklin

    Rosalind Franklin
    Rosalind Franlkin obtains x-ray diffraction images of DNA.
  • Alfred Hershey and Martha Chase

    Alfred Hershey and Martha Chase
    Alfred Hershey and Martha Chase performed "blender" experiments. They tagged bacteriophages using radioactive isotopes Phosphorous 32 and Sulfur 35.
  • James Watson and Francis Crick

    James Watson and Francis Crick
    James Watson and Francis Crick used all the known clues of DNA's structure to construct a model. The molecule could unzip.
  • Stanley Miller and Harold Urey

    Stanley Miller and Harold Urey
    Stanley Miller and Harold Urey demonstrate the formation of simple organic molecules from molecules thought to be abundant on early Earth.
  • Francis Crick and George Gamov

    Francis Crick and George Gamov
    Francis Crick and George Gamov worked out the central dogma stating that DNA transcribes into messenger RNA, which translaes into protein. Ammended in '57. mRNA.
  • Marshall Nirenberg and Severo Ochoa

    Marshall Nirenberg and Severo Ochoa
    Marshall Nirenberg and Severo Ochoa discovered specific nucleotide sequences in groups of 3 determine 20 amino acids.
  • Paul Berg

    Paul Berg
    Paul Berg cut sections of viral DNA and bacterial DNA with the same restriction enzyme. DNA was compatible and he spliced them.
  • Stanley Cohen and Herbert Boyer

    Stanley Cohen and Herbert Boyer
    Stanley Cohen and Herbert Boyer created a plasmid. Cohen's group cloned the first animal gene and placed it in a bacteria.
  • Herb Boyer

    Herb Boyer
    Herb Boyer cofounds the first bitech company, Genentech.
  • Collaborative Project

    Collaborative Project
    The first practical application of genetic engineering and clone research began.
  • Frederick Sanger

    Frederick Sanger
    Frederick Sanger developed the chain termination method for sequencing DNA.
  • Collaborative Project

    Collaborative Project
    The development of automated sequencing technology accelerates genome projects.