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Discoveries of genetics
all the men and women that discovered something that is relevant to genetics -
Friedrich Miescher
He discovered aminoacids. He called it nuclein. -
Phoebus Levene
Phoebus Levene discovered all the components of the DNA, defined the nucleotides. Although he did not get right the composition of the molecule. He suggested a model called tetrade (4 nucleotides together). -
Frederick Griffith
Accepted demonstrations of bacterial transformation. He did an experiment to prove it that was called the transformation experiment. -
Avery, MacLeod and McCarty
They explained and did the conclusion of the transformation experiment. -
Watson and Crick Inside-Out model
They came up with the double-helix model. But it was incorrect as they said that the sugar and phosphates were at the centre and that the nucleobases were facing outside. It made no chemical sense -
The triple helix
Linus Pauling and Robert Corey proposed a triple helix model for DNA. But it was incorrect too. -
Rosalind Franklin's photo 51
Rosalind Franklin did a lot of photographs of the B form of DNA. The best photo was photo 51 which was stolen by Maurice Wilkings and given to Watson and Crick. She received no credit for the discovery of the double helix correct model. -
Erwin Chargaff
He counted the nucleobases (A, T, C, G). And did the Chargaff's rules. The amount of Adenine and Thymine is always balanced with the amount of Cytosine and Guanine (in percentage). But he did not realise the importance of his results. -
Hershey-Chase experiments
They came to the conclusion that DNA was the genetic material and not the protein. They did so by using phages, one with radioactive sulfur and the other with radioactive DNA, so they could keep track of the proteins and the DNA in the cells. They separated the supernatant from the pellet using centrifugation and the radioactive proteins (sulfur) were in the supernatant, and the radioactive DNA was in the pellet. Then they did their conclusion. -
Watson and Crick second model
When Watson and Crick saw photo 51 they knew what it meant and corrected their last model. They published a paper on April 25, 1953, explaining the structure of DNA and it's double helix. -
Nobel Prize of 1962
Watson, Crick and Wilkins got the Nobel Prize in Physiology or Medicine in 1962 and Roselin Frankling did not get any credit because she passed away before the prize was given.