DNA Timeline

By kcook22
  • Friedrich Miescher

    Friedrich Miescher
    At the University of Tübingen, Miescher discovered nucleic acids while experimenting on the white blood cells in pus.
  • Oswald Avery

    Oswald Avery
    In 1907 Avery started his study by working on many strains of bacteria by applying different immunological and chemical methods. He wrote a study on tuberculosis bacterium, and did his Pneumococcus work at the Rockefeller Institute Hospital. He also theorized that genes were made up of bacteria.
  • Frederick Griffith

    Frederick Griffith
    At the Pathological library for the ministry of Health, Griffith experimented with bacteria and was the first to reveal the “transforming principle,” which led to the discovery that DNA acts as the carrier of genetic information. He used two strains of the bacterium Streptococcus pneumoniae (one strain lethal to mice and one harmless) in order to perform his experiments.
  • Erwin Chargaff

    Erwin Chargaff
    In 1949, Chargaff discovered that the proportions of bases in DNA depended on the species the DNA came from. He also discovered that in DNA from any source the amount of T was equal to A. Also, the amount of C was equal to G. Chargaff came to these conclusions through the use of partition chromatography to separate the DNA and UV spectroscopy to analyze the DNA.
  • Alfred Hershey & Martha Chase

    Alfred Hershey & Martha Chase
    At Carnegie Institute of Washington, Hershey and Chase performed a series of experiments that confirmed that genetic material was made of deoxyribonucleic acid, or DNA. They did this through performing experiments on viruses that infect bacteria. Hershey won a nobel prize in 1969 but Chase did not.
  • James Watson & Francis Crick

    James Watson & Francis Crick
    Watson and Crick used Rosalind Franklin's image of DNA to construct a model to determine the molecular structure of DNA. They both won a nobel prize in 1962.
  • Rosalind Franklin

    Rosalind Franklin
    Franklin used x-ray diffraction methods to photograph DNA. This photo helped Watson and Crick construct their model of DNA.
  • Matthew Meselson & Franklin Stahl

    Matthew Meselson & Franklin Stahl
    Meselson and Stahl experimented on bacteria cultured in a nutrient containing a heavy isotope of nitrogen, discovered the mode of replication of DNA, and determined that DNA replication was semiconservative.
  • Ian Wilmut

    Ian Wilmut
    Wilmut was a British developmental biologist who was the first to clone a Finn Dorset sheep named Dolly. He started with cultured embryonic cells that were nine days old and eventually used nuclear transfer of differentiated adult cells to create the clone.
  • Craig Venter

    Craig Venter
    Venter mapped the human genome through the use of the clone-by-clone method and eventually published the genome. He never won a nobel prize.