DNA: The Genetic Material Timeline

  • P.A. Levene- Nucleotides

    P.A. Levene- Nucleotides
    He characterized the different forms of nucleic acid, DNA from RNA, and found that DNA contained adenine, guanine, thymine, cytosine, deoxyribose, and a phosphate group
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  • Frederick Griffith

    Frederick Griffith
    Performed the first major experiment that led to the discovery of DNA as the genetic material. He studied two strains of the bacteria Streptococcus pneumoniae, which causes pneumonia. He found that one strain could be transformed into the other form.
  • Oswald Avery

    Oswald Avery
    Identified the molecule that transformed the R strain of bacteria into the S strain. Discovered that DNA is the material of which genes and chromosomes are made.
  • Erwin Chargaff

    Erwin Chargaff
    Analyzed the amount of adenine, guanine, thymine, and cytosine in the DNA of various speices. He found that the amount of guanine nearly equals the amount of cytosine, and the amount of adenine nearly equals the amount of thymine within a species.
  • Hershey and Chase Experiment

    Hershey and Chase Experiment
    A series of experiments conducted by Alfred Hershey and Martha Chase that helped to confirm that DNA was the genetic material.
  • Rosalind Franklin – X-ray diffraction

    Rosalind Franklin – X-ray diffraction
    She made critical contributions to the understanding of the fine molecular structures of DNA, RNA, viruses, coal, and graphite. The DNA work achieved the most fame because DNA plays essential roles in cell metabolism and genetics, and the discovery of its structure helped scientists understand how genetic information is passed from parents to children.
  • James Watson-DNA structure

    James Watson-DNA structure
    He proposed that the structure of DNA was a double helix and not a triple helix like Linus Pauling proposed.
  • Francis Crick- DNA stucture

    Francis Crick- DNA stucture
    Along with James Watson, he discovered the structure of DNA.
  • Maurice Wilkins

    Maurice Wilkins
    Along with James Watson and Francis Crick he helped discover the molecular structure of DNA
  • Linus Pauling

    Linus Pauling
    He proposes that DNA was a triple helix and not a double helix.