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In 1928 a scientist named Frederick Griffith was
working on a project that enabled others to point out that DNA was the
molecule of inheritance. -
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To understand the DNA molecule better scientists were trying to
make a model to understand how it works and what it does. In the
1940’s another scientist named Erwin Chargaff noticed a pattern in the
amounts of the four bases: adenine, guanine, cytosine, and thymine. thus making chargaffs rules -
when all DNA was eliminated the bacteria stopped
transforming. This discovery identifying DNA as the active agent in
transformation was the “transforming principle.” -
1952 Alfred Hershey and Martha Chase suggest that
only DNA is needed for viral replication. Using radioactive isotopes
35S to track protein and 32P to track DNA -
Two scientists named, Rosalind Franklin and Maurice
Wilkins, wanted to try to make a crystal of the DNA molecule. If
they could get DNA to crystallize, then they could make an x-ray
pattern, then making it easier to understand how DNA works. -
In 1953 two scientists, James Watson and Francis
Crick, were trying to put together a model of DNA. When they saw
Franklin and Wilkin's picture of the X-ray they had enough information
to make an accurate model. making the first correct modle of DNA