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Biotechnology Timeline P3

  • First recorded description of living cells by Robert Hooke

  • Antonie van Leeuwenhoek discovers and describes bacteria and protozoa.

  • Edward Jenner uses first viral vaccine to inoculate a child from smallpox.

  • The first recorded use of the word biology.

  • Henri Dutrochet discovers that tissues are composed of living cells.

  • Protein discovered, named and recorded by Gerardus Johannes Mulder and Jöns Jacob Berzelius.

  • Louis Pasteur discovers the bacterial origin of fermentation.

  • Gregor Mendel discovers the laws of inheritance.

  • Antonin Prandtl invents first centrifuge to separate cream from milk.

  • Friedrich Miescher identifies DNA in the sperm of a trout.

  • Ernst Hoppe-Seyler discovers invertase, which is still used for making artificial sweeteners.

  • Robert Koch develops a technique for staining bacteria for identification.

  • Walther Flemming discovers chromatin leading to the discovery of chromosomes.

  • Louis Pasteur develops vaccines against bacteria that cause cholera and anthrax in chickens.

  • Louis Pasteur and Emile Roux develop the first rabies vaccine and use it on Joseph Meister.

  • Károly Ereky, a Hungarian agricultural engineer, first uses the word biotechnology.

  • Alexander Fleming notices that a certain mould could stop the duplication of bacteria, leading to the first antibiotic: penicillin.

  • L.V. Radushkevich and V.M. Lukyanovich publish clear images of 50 nanometer diameter tubes made of carbon, in the Soviet Journal of Physical Chemistry.

  • James D. Watson and Francis Crick describe the structure of DNA.

  • The term bionics is coined by Jack E. Steele.

  • The first commercial myoelectric arm is developed by the Central Prosthetic Research Institute of the USSR, and distributed by the Hangar Limb Factory of the UK.

  • Stanley Norman Cohen and Herbert Boyer perform the first successful recombinant DNA experiment, using bacterial genes.

  • The DNA composition of chimpanzees and gorillas is discovered to be 99% similar to that of humans.

  • Scientist invent the first biocement for industrial applications.

  • Method for producing monoclonal antibodies developed by Köhler and César Milstein.

  • North Carolina scientists Clyde Hutchison and Marshall Edgell show it is possible to introduce specific mutations at specific sites in a DNA molecule.

  • The U.S. patent for gene cloning is awarded to Cohen and Boyer

  • The Polymerase Chain Reaction (PCR) technique is conceived.

  • British scientists, led by Ian Wilmut from the Roslin Institute, report cloning Dolly the sheep using DNA from two adult sheep cells.

  • Rice becomes the first crop to have its genome decoded.

  • Thirty-one-year-old Zac Vawter successfully uses a nervous system-controlled bionic leg to climb the Chicago Willis Tower.