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William Harvey discovered that blood circulates through the body and was called "the greatest physiological advance of the 17th century and perhaps of all time." He exclusively used animal experiements everything from sheep to snakes.
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Nicolas Saucerotte employed animal experiments to shed light on problems in neurosurgery.
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The Cruelty to Animals Act was passed to regulate and oversee experimentation to animals. Persons who wished to perform experiments on animals had to be licensed.
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Louis Pasteur performed a public demonstration by vaccinating twenty-four sheep, one goat, and six cows. The purpose of the demonstration was to counteract rabies.
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Max Theiler discovered that white mice could also be employed to study yellow fever.
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The National Association of Medical Research (now defunct) attempted to clarify on the virtues of medical research. The only advocacy group formed during this time.
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Animal Care Panel was formed.
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The Animal Care Panel publishes the NIH Guide which is a guide for the care and use of laboratory animals.
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President Lyndon Johnson signed the Laboratory Animal Welfare Act (LAWA) to appease the public's outrage over the theft of pets for animal research.
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The Medicines Act calls for the use of alternatives to animal testing of drugs when possible.
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Experimented on monkeys to find a vaccine for the Ebola virus and AIDS.
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The National Association for Biomedical Research (NABR), a major animal research advocacy organization throughout the 1980s and 1990s