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In 1800, Brittish chemist Davy Humphry was the first to suggest nitrous oxide as an anesthetic.
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In 1820, Henry Hill Hickman experimented with nitrous oxide as an anesthetic.
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Crawford W. Long was the first to use ether as an oral inhalable anesthetic on a patient.
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Horace Wells, an American dentist was first to use nitrous oxide in a dental operation.
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Crawford W. Long used ether as a anesthetic during child delivery.
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W.T.G. Morton used ether in an operation.
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Sir James Y. Simpson performed child births using chloroform to ease pain.
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The use of local anesthesia began.
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The use of spinal anesthesia (epidural anesthesia) had begun, but was not inducted into clinical practice until some time later.
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The use of spinal anesthesia was inducted into clinical practice.
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Medical schools began offering formal training in anesthesia.
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The study and administration of anesthesia became a seperate medical study, anesthesiology.
