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The Bubonic Plague started in China in the early 1300's .
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By 1340's the Black Plague had reached Northern Africa.
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In 1347 A.D. The Black Death Reached Europe. Scientists believe that the disease was carried over from Asia by Merchants and Soldiers.
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The Black Death was at its worst between 1348 - 1350 .
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In 1366 another wave of the Black Plague broke out
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By 1397 the Black Plague had died down. It had killed about 75 Million people whilst it raged.
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The first major smallpox outbreak happened in the 1770's and killed thousands of native Americans.
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The vaccination that stopped the smallpox virus was discovered in 1796 by Edward Jeener.
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Scientists think that in 1913 pigs started giving humans a virus which later became the Spanish Flu.
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In 1918 the Spanish Flu started and the first wave of Spanish Flu hit worldwide.
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The Second Wave of Spanish Flu hit in 1919. It came from France and the United States and had mutated and become more deadly.
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The Spanish Flu ended in 1920. It killed between 50 - 100 Million People worldwide.
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In the last few months of 1979 it was declared that smallpox had been eradicated. It only remains in four labs around the world
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Smallpox killed about 300,000 people worldwide.