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The Natchez Trace post route, following an old trail running from Nashville, Tennessee to Natchez, Mississippi, is established by an Act of Congress.
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Lydia Child is born and would become a foremost author expounding the idea of an American abolitionist.
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The Lewis and Clark Expedition to map the northwest United States ends. Essential to the journey was Sacagawea, their female Indian guide.
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James Madison is elected as the 4th President of the United States, defeating Charles C. Pinckney.
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The Pacific Fur Company is formed by John Jacob Astor.
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The first steam-powered ferry service between New York City and Hoboken, New Jersey is started on John Steven's ship, the Juliana.
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- At the battle of Tippecanoe, Indian warriors under the command of Tecumseh and his brother Tenskwatawa, known as the Prophet, are defeated by William Henry Harrison, the governor of Indiana.
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Second Bank of the United States is chartered, five years after the expiration of the 1st Bank of the United States.
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The flag of the United States is officially adopted by Congress with the configuration of thirteen red and white stripes and one star for each state in the union. At the time of adoption, with the most recent addition of Mississippi, the flag had twenty stars.
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The first United States warship to navigate the world, the U.S.S. Vincennes, leaves New York City under the command of William Finch.
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Martin Van Buren, as President, and Richard M. Johnson, Vice President, are inaugurated into office.
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The Indian Frontier Post, Fort Scott, in Indian Territory (Kansas) is evacuated by the United States Army riflemen
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The USS Monitor won the battle against the Confederate ironclad Virginia off the coast of Hampton Roads, Virginia
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Thomas Edison and Alexander Graham Bell form the Oriental Telephone Company.
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Work begins on the first motion picture camera at Thomas A. Edison's laboratory.
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The first issue of the Wall Street Journal is published.
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The first recital of the Pledge of Allegiance in U.S. public schools is done to mark the 400th anniversary of Columbus Day.
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