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The Black Death was a plague pandemic that devastated medieval Europe between 1347 and 1352.
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Filippo Brunelleschi (1377-1446) was an Italian architect, goldsmith and sculptor of the Renaissance; Most famous for his work on the Florence Cathedral: its impressive brick dome rising towards the heavens, which was completed in 1436.
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Johannes Gutenberg (Mainz, Holy Roman Empire; c. 1400 - Mainz, February 3, 1468), was a German goldsmith, inventor of the modern printing press with movable type, around 1450
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The Siege of Orleans (October 12, 1428 – May 8, 1429) marked a turning point in the Hundred Years' War between France and England.
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The Birth of Venus, one of Botticelli's most recognized paintings, depicts the birth of the goddess of love Venus emerging from the sea foam as a fully mature woman. 1485-1486
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The School of Athens (Italian: Scuola di Atene) is one of the most notable paintings by the Italian Renaissance artist Rafael Sanzio. The School of Athens represents the value of scientific thought and natural truth, whose development is attributed to classical antiquity. 1509-1511
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1513: Niccolò Machiavelli publishes The Prince. Often considered the most influential political book of all time, The Prince makes the argument that it is better for a ruler to be feared than loved.
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The coronation of Elizabeth I as queen of the Kingdom of England took place in Westminster Abbey, London, on January 15, 1559.