File 000 (3)

The discovery of DNA - Kubica, Kenzie

  • Friedrich Miescher

    Friedrich Miescher

    determined that DNA is not a protein and that it is rich in nitrogen and phosphorus, but he never learned its function
  • Frederick Griffith

    Frederick Griffith

    discovered that heat destroyed the ability of lethal S bacteria to cause pneumonia, but it did not destroy their hereditary material, including whatever specified “kill mice.” That material could be transferred from dead S cells to live R cells, which put it to use.
  • Oswald Avery,  Maclyn McCarty & Colin McCleod

    Oswald Avery, Maclyn McCarty & Colin McCleod

    Identified “transforming principle.” They extracted lipid, protein, and nucleic acids from S cells then used a process of elimination to determine which transformed bacteria. Treating the extract with enzymes that destroy lipids and proteins did not destroy the transforming principle
  • Barbara McClintock

    Barbara McClintock

    using corn as a model organism she discovered that genes can move around chromosomes. these mobile genes units are called transposons and are found in many species
  • Alfred Hershey & Martha Chase

    Alfred Hershey & Martha Chase

    proved that DNA, and not protein, satisfies the first expected property of a hereditary molecule: It transmits a full complement of hereditary information.
  • Erwin Chargaff

    Erwin Chargaff

    discovered that the proportions of bases in DNA depend on the species the DNA comes from
  • Rosalind Franklin & Maurice Wilkins

    Rosalind Franklin & Maurice Wilkins

    revealed the physical and chemical basis of how characteristics are passed down through the generations and how they are expressed in individual organisms.
  • Matthew Meselson & Franklin Stahl

    Matthew Meselson & Franklin Stahl

    demonstrate that DNA replicates semi conservatively
  • James Watson & Frances Crick

    James Watson & Frances Crick

    described the double helix structure of DNA.
  • Linus Pauling

    Linus Pauling

    known as the founder of molecular biology due to his discovery of the spiral structure of proteins
  • Paul Berg

    Paul Berg

    succeeded in inserting DNA from a bacterium into the virus's DNA.
  • Frederick Sanger

    Frederick Sanger

    developed rapid DNA sequencing methods. colored dyes are used to identify each of the nucleic acids that make up DNA
  • Kary Mullis

    Kary Mullis

    invented the process known as polymerase chain reaction (PCR), in which a small amount of DNA can be copied in large quantities over a short period of time.
  • J. Craig Venter

    J. Craig Venter

    known for leading the first draft sequence of the human genome and assembled the first team to transfect a cell with a synthetic chromosome.