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The Microscope is Brought to Life
Hans Jansen and his son, Zacharias, become the first to have any sort of documentation that supports that they created the idea of the microscope. -
The Jansen Design
Hans and Zacharias Jansen invent their own design of the microscope (compound microscope) that could only be used for opaque objects and has a magnification of 20x. -
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The Development of the Microscope and Cell Theory
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First Publication of "Microgphia"
With the help of his own microscope, Robert Hooke, the Secretary of Royal Society, publishes a folio of thirty-eight copper-plate illustrations of objects drawn titled, "Microgphia". -
First Discovery of Cells
Antony van Leeuwenhoek, a tradesman of Delft, Holland, discovered bacteria, free-living and parasitic microscope protists, sperm cells, blood cells, and more, using only a device that magnified up to 300x. -
Protozoa
Antony van Leeuwenhook observed what he called "little animals" (protozoa) through a microscope. -
Achromatic Lenses are Introduced
Achromatic lenses provided a resolution of 1 micron or 1/1000 millimeters. -
Discovery of the Nucleus
The nucleus is discovered by Robert Brown. -
The Cell Theory
The Cell Theory is formally proposed by Theodor Schwann and Matthias Schleiden. -
Publication of "Microscopic Investigations on the Accordance in the Structure and Growth of Plants and Animals"
Theodor Schwann publishes the book, "Microscopic Investigations on the Accordance in the Structure and Growth of Plants and Animals," in which includes the first statement of cell theory: All living things are made up of cells. -
Rudolf Virchow
Rudolf Virchow, based off the work of Schleiden and Schwann, proposes that all living cells must rise from pre-existing cells. -
Ernst Abbe's Theory of the Microscope
Ernse Abbe publishes his own theory of the microscope, clearly explaining the difference between magnification and resolution. -
Discovery of Mitosis
Mitosis is discovered by Walther Flemming. -
Apochromatic Objective is Designed
Ernst Abbe designs the aprochromatic objective lenses, which brings red, yellow, and blue into one single focus. -
First Commercial UV Microscope
Zeiss invents the first commercial UV microscope in which the resolution, based off of Abbe's formula, is twice that of a visible light microscope. -
How to View Unstained Cells
Frank Zernike discovers how to view unstained cells using the phase angle of rays. -
First Electron Microscope is Constructed
The first electron microscope is contructed by Max Knoll and Ernst Ruska.
