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Hans Jansen and his son, Zacharias, become the first to have any sort of documentation that supports that they created the idea of the microscope.
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Hans and Zacharias Jansen invent their own design of the microscope (compound microscope) that could only be used for opaque objects and has a magnification of 20x.
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With the help of his own microscope, Robert Hooke, the Secretary of Royal Society, publishes a folio of thirty-eight copper-plate illustrations of objects drawn titled, "Microgphia".
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Antony van Leeuwenhoek, a tradesman of Delft, Holland, discovered bacteria, free-living and parasitic microscope protists, sperm cells, blood cells, and more, using only a device that magnified up to 300x.
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Antony van Leeuwenhook observed what he called "little animals" (protozoa) through a microscope.
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Achromatic lenses provided a resolution of 1 micron or 1/1000 millimeters.
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The nucleus is discovered by Robert Brown.
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The Cell Theory is formally proposed by Theodor Schwann and Matthias Schleiden.
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Theodor Schwann publishes the book, "Microscopic Investigations on the Accordance in the Structure and Growth of Plants and Animals," in which includes the first statement of cell theory: All living things are made up of cells.
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Rudolf Virchow, based off the work of Schleiden and Schwann, proposes that all living cells must rise from pre-existing cells.
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Ernse Abbe publishes his own theory of the microscope, clearly explaining the difference between magnification and resolution.
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Mitosis is discovered by Walther Flemming.
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Ernst Abbe designs the aprochromatic objective lenses, which brings red, yellow, and blue into one single focus.
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Zeiss invents the first commercial UV microscope in which the resolution, based off of Abbe's formula, is twice that of a visible light microscope.
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Frank Zernike discovers how to view unstained cells using the phase angle of rays.
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The first electron microscope is contructed by Max Knoll and Ernst Ruska.
