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Plague breaks out in central Asia, infecting Mongol hordes.
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Plague spreads to Constantinople, a major port city, through silk trade routes
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The plague is brought to Sicily by a ship from the east
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The plague is brought to Syria, Palestine, Egypt, northern Africa, Greece, France, and Spain through shipping trade
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The plague is brought to France, where the pope lives, and Britain
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By this time, the plague had killed about 25 million people, a third of its population.
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Most of the rulers are dead. workers and peasants revolt against remaining government, causing the end of feudalism and beginning of middle class.
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Giovanni Boccaccio finishes writing The Decameron, a fictional story that describes the 1348 outbreak of the Black Death in Florence, Italy.
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Another plague breaks out in London, infecting many and killing 43.
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A huge fire engulfs London, killing most of the infected rats, fleas, and people and taking the plague with it.