-
Christopher Columbus
reaches the Americas, landing on an island in the Bahamas. This marks the beginning of Spanish exploration and colonization. -
Columbus undertakes three more voyages to the Caribbean, exploring various islands including Hispaniola, Cuba, and Puerto Rico.
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Juan Ponce de León
begins the conquest of Puerto Rico. -
Diego Velázquez de Cuéllar
starts the connuest of Cuba. -
Hernán Cortés lands on the coast of Mexico and begins his expedition towards the Aztec capital, Tenochtitlan.
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Cortés captures
Tenochtitlan, leading to the fall of the Aztec Empire and the establishment of Mexico City. -
Francisco Hernández de Córdoba and Gil González Dávila start the conquest of Nicaragua.
-
Pedro de Alvarado begins the conquest of Guatemala.
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Francisco Pizarro starts
his expedition to Peru. -
Pizarro captures the Inca emperor Atahualpa and subsequently conquers the Inca Empire.
-
Pedro de Mendoza
establishes Buenos Aires in Argentina. -
Sebastián de
Belalcázar conquers parts of Colombia and Ecuador. -
Santiago is founded in Chile by Pedro de Valdivia.
-
Francisco Vázquez
de Coronado explores the southwestern United States. -
The Spanish establish the Viceroyalty of Peru.
-
Pedro Menéndez de Avilés
founds St. Augustine in Florida, the oldest continuously inhabited European-established
settlement in the continental
United States.