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It was the first major pandemic, attacking the Byzantine Empire. The bacterium responsible was identified as your "Sania Pestis" or as well, as bubonic plague, a pathogen carried by rats and transferred to humans through fleas.
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25 to 50 million people died, which was about quarter of the Earth's population then.
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The plague returned with a vengeance as the most infamous pandemic in human history.
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Sailors returned to Sicily with a mysterious illness that formed dark swellings or buboes on the armpits and groin. Venetians banned sailors from entering their cities for 40 days, in Italy they called this Cuarenta G or Denis (beginning of the word quarantine.) This method helped, although, this illness took up 200 million lives across Eurasia.
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During this illness, they also had to endure many diseases like measles chicken pox and smallpox. Colonization appeared and this sickness spread, making many deaths.
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The most recent mass pandemic struck and infected 500 million worldwide. This impacted young adults hardest, half of those who died were in their 20s and 40s.
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99% were under the age of 65. By the end it claimed the lives of 50 to 100 million.
