Microscopes and the Development of Cell Theory

  • Zacharias and Hans Janssen invent the compound microscope.

  • Robert Hook presented his work "Micrographia"

    This Included sketches observe cork cells used simple microscopes to find them.
  • Antony van Leeuwenhoek discovered bacteria, free-living and parasitic microscopic protists, sperm cells, blood cells and more.

    Used a microscope at can zoom 300x
  • Antoni van Leeuwenhook reported that he had observed "little animals" -- protozoa -- through a microscope.­

  • Chester Moore Hall invented achromatic lenses for spectacle

  • Achromatic lenses were invented which provide resolution of 1 micron or 1/1000 mm

  • Schlieden and Schwann published a book which stated "All living things are made up of cells"

    That statement was the first statement of the cell theory. The published work was called "Microscopic Investigations on the Accordance in the Structure and Growth of Plants and Animals" He reached his conclusion while studying animal tissues,
  • Cells were finally acknowledged into the basic units of life

  • Kolliker descibes mitochondria in muscle

  • Rudolf Virchow proposed that all living cells must rise from pre-existing cells.

  • Ernst Abbe published his work on the theory of the microscope.

  • Walther Flemming discovers mitosis.

  • Koch uses aniline dyes to indentify bacteria causing TB and cholera

  • Golgi stains cells with white nitrate, discovering its apparatus

  • Fritz Zernike discovered that unstained cells can be viewed using the phase angle of rays based on visible light

  • Max Knoll and Ernst Ruska invent the first electron microscope.

  • Fritz Zernike invented the phase contrast microscope

  • First electron micrograph of a biological sample was introduced

    It was a long-leaved sundew fixed with osmium.
  • The commercial microscope by Fritz Zernike was brought to the market.

  • DIC sytem was patented by Nomarsky

  • 1st commercial scanning electron telescople was invented