Microbiology's Evolution By Colombo Student Mar 9, 1600 Microscope was available Sep 9, 1670 1670-1723: Anton van Leeuwenhoek Sep 9, 1850 Louis Pasteur Denied spontaneous generation Sep 9, 1859 Louis Pasteur: Germ theory of disease Sep 9, 1860 Robert Koch: proof of Pasteur's theory Sep 9, 1940 Electron Microscope was developed Sep 9, 1942 World War ll: Antibiotics Sep 9, 1950 Vaccines appear Sep 9, 2016 Contemporary Microbiology