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In 1616 he announced his discovery of the circulation of blood within the body.
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His most famous written work was ‘De Sedibus et Causis Morburum Per Anatomen Indagatis’ (On the Sites and Causes of Diseases) published in 1761.
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He took some pus from cowpox blisters found on the hand of a milkmaid called Sarah. She had milked a cow called Blossom and had developed the tell-tale blisters. Jenner ‘injected’ some of the pus into James. This process he repeated over a number of days gradually increasing the amount of pus he put into the boy. He then deliberately injected Phipps with smallpox. James became ill but after a few days made a full recovery with no side effects. It seemed that Jenner had made a brilliant discovery
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