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The Corps of Discovery leaves Camp Wood and begins its journey up the Missouri River "under a gentle breeze."
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The Corps enters the Great Plains and sees animals unknown in the eastern United States.
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Lewis and Clark hire French-Canadian fur-trader Toussaint Charbonneau and his Shoshone wife, Sacagawea, to act as interpreters on the journey ahead.
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Lewis and Clark send a shipment of artifacts and specimens to President Jefferson; the "Permanent Party" heads west.
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The Corps reaches the White Cliffs region of the Missouri River.
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The expedition reaches the Columbia River, the last waterway to the Pacific Ocean.
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After a winter of only 12 days without rain, the men present their fort to the Clatsop Indians and set out for home.
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Having found an easier route across the country, the men reach St. Louis nearly two and a half years after their journey began and are acclaimed as national heroes.