First exploratory visit by JHU faculty to Bangladesh to establish collaboration with BIRPERHT and USAID mission in Dhaka
Meeting with MOHFW to discuss maternal nutrition research
Gaibandha and Rangpur are selected as study sites
USAID Mission expresses interest in the nutrition trial to MOHFW
National Technical Committee (NTC) is established by MOHFW
Study protocol and draft forms are submitted to Bangladesh Medical Research Council (BMRC) for ethical review and approval
Start of field work (mapping of households and 'sector' defining)
Implementation Agreement signed between BIRPERHT and the GOB
Study management established and staff recruited/trained
JiVitA-1 protocol submitted to JHU CHR
Study sectors randomized to 3 treatment codes
Protocol approved by BMRC
Protocol approved by JHU CHR
Study sectors profiled and surveyed
Enumeration of married women for inclusion in JiVitA (JiVitA weeks 28-32)
Five weekly, community-based pregnancy surveillance with urine-test verifications initiated (JiVitA week 33)
supplementation of pregnant women by treatment code begun (week 34))
Five weekly surveillance (PSF) begun
JiVitA is formally registered as a Project under the National Integrated Population and Health Program (NIPHP) under the Strategic Objective between the GOB and US Government
JiVitA-1 'Substudy' is launched
JiVitA-1 sample size increased from 54,000 to 68,000 pregnancies
Re-consent process for all pregnant participants
JiVitA-1 dataset frozen for DSMB-1 analysis (JiVitA week 130)
MoU with Institute of Nutrition and Food Sciences (INFS) Urinary Iodine Study
Barbara Seligman (USAID-Wash) visits JiVitA
MoU for collaboration with Bangladesh Atomic Energy Commission (BAEC)
Bacterial Vaginosis Substudy
GIS survey begins
First DSMB meeting
Birth defect verification process begins
JiVitA first public introduction at ASCODD conference
Consent for JiVitA-2 begins
JiVitA-2 supplementation begins
John Rogosh (USAID-Wash) visits JiVitA
JiVitA training practicum (INFS students-Batch 1)
Referral system initiated
JiVitA training practicum (Pakistan students)
GIS survey completed
JiVitA training practicum (INFS students-Batch 2)
JiVitA-1 dataset frozen for DSMB-2 analysis
IVBA training for RPs at Dhaka Shishu Hospital
KISHORI study begins (Baseline Adolescent Census)
Second DSMB meeting
National Technical Advisory Panel meeting
randomization of sectors
JHSPH IRB Pre-approval (pending BMRC clearance)
BMRC conditional approval obtained
JHSPH IRB approval to begin trial
Enumeration of reproductive age women begins
Pregnancy enrollment interviews begin
No objection certificate for Pre-mix import into country
Receipt of pre-mix & delivery to BEXIMCO (supplement manufacturer)
Receipt of tablets by JiVitA
Supplementation for enrolled women from the 12th week of gestation
Newborn dosing of infants born to enrolled women begins
BMRC unconditional approval obtained (to supplement in 1st trimester)
