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Europeans introduced sugarcane to the New World in the 1490s http://bell.lib.umn.edu/Products/sugar.html
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This year was when the Columbian Exchange was initiated. http://www.shmoop.com/columbian-exchange/timeline.html
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Conquistador Hernan Cortes, leading a small army of a few hundred soldiers on horses, arrived at the Aztec capital of Tenochtitlian. http://www.shmoop.com/columbian-exchange/timeline.html
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Small Pox was spread by a soldier in the Cortes army, and ended up infecting at least half of the citizens in Aztecs capital city in Tenochtitlan. http://www.shmoop.com/columbian-exchange/timeline.html
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Small Pox made its way to the Inca Empire, wiping out more than 200,000 people. http://www.shmoop.com/columbian-exchange/timeline.html
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Francisco Pizarro got his ransom demands from the Inca ruler Atawallpa including one room filled with gold and two filled with silver. http://www.shmoop.com/columbian-exchange/timeline.html
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Hernando De Soto and his party of 600 men (with at least as many livestock) landed on the Gulf Coast of America in their expidition of conquest into North America lands. http://www.shmoop.com/columbian-exchange/timeline.html
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La Salle canoed the length of the Mississippi River, where he found carefully tended fields of corn, abd an almost unhabited wilderness with many buffalo. http://www.shmoop.com/columbian-exchange/timeline.html
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The Comanche fully integrate horses within this year. http://www.shmoop.com/columbian-exchange/timeline.html
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potatoes became very important to the irish this year. It was originally cultivated in South America. http://www.shmoop.com/columbian-exchange/timeline.html