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The earliest known clone produced by scientific manipulation was created in the year 1885. The German scientist Hans Driesch created identical twins from a single sea urchin embryo by a process called embryo splitting
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scientists could take a nucleus from an early embryonic cell and successfully transfer it into an unfertilized and enucleated egg cell.
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Bromhall conducted experiments using rabbit embryos and showed that, after a certain stage in development called the morula stage, embryos produced from nuclear transfer died. Bromhall hypothesized that they died as the result of complications from the punctures made in the cell membrane during the transfer
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British developmental biologist Ian Wilmut generated a cloned sheep, named Dolly, by means of nuclear transfer involving an enucleated embryo and a differentiated cell nucleus
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The lambs born from this procedure were named Megan and Morag. This experiment showed that cultured cells can supply donor nuclei for cloning by nuclear transfer
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The successful cloning of rhesus monkeys was first reported back in 1997, utilizing blastomeres from early-stage embryos as donor cells. This experiment showed that primates, humans’ closest relatives, can be cloned.
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the world's first cloned endangered species, an Asian ox known as a guar, was born to a domestic cow. Although the calf died just a few days later due to an infection
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successful derivation of human embryonic stem cell lines derived through SCNT, using fetal and infant donor cells. Using MII oocytes from volunteers and their improved SCNT procedure, human clone embryos were successfully produced.