Dna

Big Shots in DNA

  • Friedrich Miescher

    Friedrich Miescher
    Collected a lot of pus from bandages from the hospital. He isolated "nuclein," DNA with associated proteins, from cell nuclei.He was also able to isolate nuclein from other cells and later used salmon sperm. Importanat because it furthered our understandings on white blood cells.
  • Thomas Morgan Hunt

    Thomas Morgan Hunt
    Used fruit flies to make important discoveries on genetic and chromosomal inheritance Importance: Contributed to genetics and inheritance in the 1900's.
  • Barbara Mcclintock

    Barbara Mcclintock
    Demonstrated the first direct physical basis for genetic ‘crossing over” on corn The crossing over worked the same way it did on hunt’s fruit flies. Importnace: Because of cross-over we figured out order of genes and distances between genes.
  • Oswald Avery

    Oswald Avery
    Did series of experiments using pneumococcus bacteria which causes pneumonia. Noticed different strains of pneumococcus could be cultured from one patient. Importanat because it helped further our understanding on diseases.
  • Erwin Chargaff

    Isolated different organisms and measured the levels of each nitrogen base. he saw that Adenine and thymine were close amounts of nucleotides and same with guanine and cytosine.Important because it helps you know the basic facts you have to know to construct an accurate model of the DNA double helix
  • Rosalind Franklin

    Produced the X-ray crystallography unit in Kings college in london. Important because she helped confirm watson and cricks theory.
  • Hershey-Chase

    Conducted a series of experiments to see which component entered the bacteria for infection. Found out dna is genetic material. Important because it helped the understanding of DNA.
  • James Watson and Francis Crick

    James Watson and Francis Crick
    Came up with the double helix structure for DNA. Important because it helped put together the dictionary by which the four-letter nucleic acid language is translated into the twenty-letter protein language.
  • Seymour Benzer

     Seymour Benzer
    Hatched his plan to get inside the gene by using bacteriophage with mutant rII genes. Important because it contributed to molecular genetic understandings.
  • Roy Britten and David Kohne

    Roy Britten and David Kohne
    Looked at reassociation rates of DNA strands and found out that mice cells contain multiple copies of very similar DNA sequences. Important becuase it helped further our undertsanding about animal DNA.
  • Stanley Cohen And Herbert Boyer

    Stanley Cohen And Herbert Boyer
    Experiment used techniques to cut and paste DNA to create the first custom-made organism containing recombined or "recombinant" DNA. Importance: made a new process to recomind DNA.