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Injected mice with heat-killed, disease-causing bacteria that “transformed” harmless bacteria into ones that can cause disease.“transforming factor” lead to question that maybe DNA carried the genetic information.
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Taking samples of DNA from various organisms and measuring the percentages of nucleotides present. Chargaff’s Rule; base pairing: adenine pairs with thymine and guanine pairs with cytosine-though he did not know why!
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Followed/repeated Griffith’s experiment. Yes, DNA stores and transmits genetic information from generation to the next.
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Taking samples of proteins from various organisms. The structure of a class of proteins is a helix.
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Used different radioactive markers to label the DNA and proteins of bacteriophages. Genetic material was DNA, not protein.
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Using X-ray technique to take pictures of DNA. Developed the technique called X-ray diffraction, which lead to the discovery of the double helix shape of DNA.
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Be researching others work and manipulating models. DNAs structure is a double helix.
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Measurements, observations, and repeating of others discoveries. Showed the existence of messenger RNA (mRNA).
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Measurements, observations, and repeating of others discoveries. Developed methods to read the DNA sequence.
