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Johann Friedrich Miescher discovers a weakly acidic substance in human nuclei he calls nuclein. It is latercalled DNA.
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Linus Pauling discovered that many proteins take the shape of an alpha helix, spiraled like a spring coil
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Base pairing almost unwraveled by Erwin Chargoff
http://www.nobelprize.org/educational/medicine/dna_double_helix/readmore.htmlErwin Chargoff shows that even though all organisms have different amounts of DNA, the amount of Adenine is always the same as the amount of Thymine -
Wilkins and Gosling took the first images of DNA, producing pictures of X-ray diffraction in aligned fibres of DNA (the double helix)
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Watson and crick propose a 3 Helical model of DNA
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Rosalind Franklin Hired to improve X-ray crystallography
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Linus Pauling proposes a triple stranded Helix structure for DNA
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Rosalind franklin uses X-ray diffraction to take photos of DNA. The patterns produced on the film by bouncing X-rays allowed the reconstruction of the 3-dimensional structure of the DNA molecule
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Rosalind Franklin's 'Photograph 51' revealed the double helical structure of DNA to Watson & Crick
[www.nobelprize.org/educational/.../dna_double_helix/readmore.html](www.nobelprize.org/educational/.../dna_double_helix/readmore.html)Crick and Watson proposed that the structure of DNA was a winding helix in which pairs of bases (adenine paired with thymine and guanine paired with cytosine) held the two strands together -
Both Wilkins and Franklin published papers on their X-ray data in the same Nature issue with Watson and Crick's paper on the structure of DNA.
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The central dogma of molecular biology was first articulated by Francis Crick
http://en.wikipedia.org/wiki/Francis_CrickThe central dogma of molecular biology deals with the detailed residue-by-residue transfer of sequential information. It states that such information cannot be transferred back from protein to either protein or nucleic acid. -
Watson and Crick won the Nobel Prize for Physiology and Medicine
http://www.nobelprize.org/educational/medicine/dna_double_helix/readmore.htmlTheir Co- discoverer Rosalind Franklin did not receive any recognition in the award as it is not given posthumously