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The first case of the Bubonic Plague that has been recorded was in China in the year 224 B.C.E.
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The first true outbreak of the plague wasn't until the 1330's in China. It spread to a port town, and because of this made it to England.
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The plague made its way to Europe on an Italian trade ship that docked in Sicily, soon infecting the city and moving through the rest of Europe.
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The plague receded for a few years in 1353, but did not leave. There were still small outbreaks, but nothing near what was to come. This was just a moment of peace that stayed for about 200 years.
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The full force of the plague return to Europe by appearing again in England. This huge outbreak markes the beginning of the Bubonic Plages most well-known time of existence.
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Throughout these years the plague infected anywhere from 10-30 percent of England, 35-69 percent in Italy, and a large number in Germany.
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Possibly the largest amount of people in a single city to be killed by the Bubonic Plague in one outbreak, 40% of the city of Marseille, France was lost in 1720.
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Working individualy, both Shibasaburo Kitasato and Alexandre Emile Jean Yersin discovered the part of the Bubonic Plague that caused it to be contagious.
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The last outbreak of the Bubbonic Plague in the U.S. today was in Los Angeles in the years 1924 and 25.
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While there have been advances in what we know about the Bubonic Plague, there is not yet a public vaccine in use. While most first-world countries are safe from another outbreak, Madagascar has been getting outbreaks almost yearly.
