16th Century By mestevaf Apr 22, 1451 Birth of Isabella Castile I Mar 10, 1452 Birth of Fernando de Aragon Jul 20, 1454 Coronation of Enrique IV Oct 19, 1469 Wedding of Isabel and Fernando Dec 13, 1474 Isabel coronation Dec 14, 1474 Death of Enrique IV Jan 1, 1475 War of the Castilian Succession Sep 4, 1478 The catholic monarchs stablish the "Santa inquisición" Sep 4, 1479 The Treaty of Alcáçovas Nov 6, 1479 Birth of Juana Jan 2, 1492 Taking of Granada name Mar 31, 1492 Expulsion of the Jews Oct 12, 1492 Discovery of America Oct 21, 1496 Wedding of Juana and Felipe Hermoso Feb 24, 1500 Birth of Charles 1st from Spain Mar 10, 1503 Birth of Ferdinand I Nov 26, 1504 Death of Isabel Nov 26, 1504 Juana's coronation Sep 25, 1506 Charles inherits his father's territories, including the Netherlands, Austria, and Spain. Sep 25, 1506 Death of Felipe Hermoso Jan 23, 1516 Death of Fernando the Catholic Nov 16, 1516 Charles I becomes King of Castile Oct 31, 1517 Martin Luther's 95 Theses spark Protestant Reformation Jun 28, 1519 Charles is crowned as Charles V, Holy Roman Emperor. Mar 19, 1520 He is crowned king of Aragon and the Two Sicilies. Apr 16, 1520 The War of the Communities begins in Castile May 25, 1521 Charles condemns Luther Feb 24, 1525 Battle of Pavia Mar 19, 1526 Charles marries Isabel from Portugal May 21, 1527 Birth of Philip II Jun 5, 1527 Sack of Rome Jun 1, 1535 Charles conquers Tunis from the Ottomans May 1, 1539 Death of Isabel de Portugal Sep 25, 1555 Peace of Augsburg 1556 Charles abdicates Philip II, his son receives Spain, the Netherlands, Naples, and the Americas Ferdinand I, his brother receives the Holy Roman Empire Aug 10, 1557 Battle of St. Quentin Spanish victory over France Mar 12, 1558 Carlos gives the Holy Empire to his brother Fernando I 1562 Philip moves the capital to Madrid Jul 25, 1564 death of Ferdinand I 1568 Dutch Revolt Oct 7, 1571 Battle of Lepanto 1580 Iberian Union: Philip becomes King of Portugal 1588 Spanish Armada 1598 Death of Philip II; succeeded by Philip III