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The general concept of Trephination is to create a hole in the skull and leave it open, thereby increasing the volume of the blood flowing to the brain.
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The U.S. Public Health department experimented on black impoverished shareholders with syphilis. They didn't inform them they had syphilis nor did they provide any type of counseling or treatment.
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Nazis experimented on those not born of pure Aryan lineage. Such experiments involved sleep deprivation, starvation, and unnecessary surgeries without anesthesia.
