-
The discovery was made.
anti-inflammatory drugs
simple screening test for new chemical
compounds -
Aspirin and phenylbutazone were available.
Objective:
1.To develop a drug to treat rheumatoid
arthritis (inflamed joints)
2.To have a superior profile both in terms of
potency and toxicity to these two drugs. -
compound code named BTS 8402 is given a
clinical trial (i.e. a trial on patients).
no better than aspirin. -
A patent is filed for the compound
2-(4-isobutylphenyl) propanoic acid
later called ibuprofen. -
Further Developement
-
Northern General Hospital in Edinburgh
anti-inflammatory effect in patients -
Clinical trials of Ibuprofen are launched in
the UK on prescription only. -
approved by the FDA
-
approved for sale in
the US and other
states and its
treatment considered
effective -
available without prescription.
-
Ibuprofen Developing Till This Day