Timeline Project By Logan Spencer 1816 René Leanne invented the Stethoscope 1818 James Blundell performed the first successful blood transfusion 1820 The first printing of the U.S. Pharmacopeia 1820 Pierre Joseph Pelletier and Joseph Bienaimé Caventou first isolated Quinine from the quinquina trees bark 1829 Charles Henri Leroux first isolated the “miracle” drug Salicylic acid, or proto-aspirin 1843 Oliver Wendell Holmes found the cause of puerperal fever 1844 Horace Wells first demonstrated nitrous oxide as an anesthetic 1845 John Hughes Bennet first described leukemia as a blood disorder 1847 Charles Babbage first devised the ophthalmoscope