• 1519

# Magellan proves that earth is round

Magellan is known to be at the origin of the first circumnavigation in history
• # François Viète develops the first symbolic notation of parameters in algebra

François Viète's was a French mathematician whose work on new algebra was an important step towards modern algebra, due to its innovative use of letters as parameters in equations
• # Galileo's telescopic observations

Galileo's first astronomical observations with a telescope (satellites of Jupiter - craters of the moon - sunspots).
• # René Descartes the 3 essays of the Discourse of the Method

René Descartes promotes intellectual rigour in Discours de la méthode pour bien conduire sa raison, et chercher la vérité dans les sciences and introduces the Cartesian coordinate system in its appendix La Géométrie (published in Leiden)
• # Robert Boyle's law of ideal gases

Boyle's law is an experimental gas law that describes how the pressure of a gas tends to decrease as the volume of the container increases
• # Robert Hooke discovers the cell

Hooke's 1665 book Micrographia, describing observations with microscopes and telescopes, as well as original work in biology, contains the earliest of an observed microorganism, a microfungus Mucor
• # Issac Newton laws of motion and gravitation

Isaasc Newton formulated the laws of motion and universal gravitation that formed the dominant scientific viewpoint until it was superseded by the theory of relativity
• # Daniel Gabriel Fahrenheit mercury thermometer

Daniel Gabriel Fahrenheit manufactures meteorological instruments like barometers, altimeters and thermometers
• # William Harvey works on blood circulation

William Harvey was the first known physician to describe completely, and in detail, the systemic circulation and properties of blood being pumped to the brain and the rest of the body by the heart,
• # Ander Celsius's Thermometric scale

Ander Celsius built a thermometer that would bring him worldwide fame. Initially, his thermometer was graduated so that "0" corresponded to the boiling point of water, and "100" to the solidification point. This scale was therefore graduated in the opposite direction to the centigrade scale we know today.