time line By Vered Ostfeld Mar 18, 2011 Daraa, March 18 The beginning of the uprising Aug 21, 2012 August 21 The U.S declared the use of chemical weapons as “red line” Aug 21, 2013 Ghouta, August 21 The Asad regime used chemical weapons against its own people Sep 14, 2013 September 14 Diplomatic agreement between Russia and the U.S.