Minute by minute Immune system response By O.Ltwich Jan 1, 2016 Allergen is ingested Jan 2, 2016 IgE antibody is formed and attaches itself to cells Jan 3, 2016 Allergic reaction begins and sends out signals for the body to release large amounts of histamine. Feb 1, 2016 Allergic reaction This causes irritation and swelling in certain areas of the body - an allergic reaction. Feb 5, 2016 Mouth : Swelling of tongue, and lip irritation begins Feb 10, 2016 Airways: difficulty breathing and wheezing Mar 3, 2016 Digestive tract: Diarrhea, vomiting and indigestion Mar 31, 2016 Skin: Hives or eczema