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Chronological history of protein engineering

By arz_victoria

  • novel protein domain fusion

  • novel protein folds

  • engeneering protein binding specificity

  • engeneering protein increased thermoshbility

  • redesign of RNA protein bindings specific

  • redesign of catalytic activity

  • enzyme catalytic redesigh

  • bimolecular enzymatic catalytic

  • Directed evolution

    Directed evolution by using iterative saturation mutagenesis based on multiresidue sites

  • Creating molecular peptide assembly machine

  • The first artificial enzymes

  • Discovery of the hormone asprosin

    Reference

  • The mammalian circadian clock

    Identified additional protein components that control the mechanism of self-sustaining "hours" inside the cell.

  • Phage display of peptides and antibodies