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Commonly know as Bobonic plague it was a pathogen carried by rats and transferred to humans through fleas.25 to 50 million people died, around a quarter of Earth's population then.
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The vengeance of bubonic plague. The venetians banned theri sailors for 40 days, her comes the word Quarentine. 100-200 million dead a third part of the world population then.
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Europeans got this illneses, it provoques hives in the body skin, when europeans arrived to America they bring it. 20 million dead, over 90% of columbia prepopulation then
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A strong Flu that affected young adults. Arund 1920 spanish flu calmed and killed 50-100 million people. 4% of global population