-
Hernando de Soto and his party become the first Europeans to reach Missouri.
-
French explores Jacques Marquette and Louis Jolliet reach Missouri
-
Slaves are brought in Missouri to mine lead.
-
Ste. Genevieve becomes the first permanet European settlement in Missouri.
-
In 1763 Sy. Louis was founded.
-
Missouri becomes the first slaveholding state to end slavery.