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On April 23, 1519, Leonardo, ill for several months, wrote his will before a notary of Amboise.
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May 2, 1519, Castle of Clos-Lucé, Amboise, France,for natural causes.
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Ian Giacomo Caprotti da Oreno, 49 called il Salaino the imp Salai, was described by Giorgio Vasari as "a nice and beautiful young man with fine, curly hair, which delighted Leonardo.
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It does not seem that Leonardo had done any painting from this drawing, but a fairly close picture is The Virgin, the Child Jesus and Saint Anne.
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It is also the time when he began to work in La Gioconda (1503-1506, and later 1510-1515), a work usually considered as a portrait of Lisa Gherardini.
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Leonardo da Vinci had many friends who enjoyed recognition in their respective fields or had an important influence in his time.
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He thinks above all of the technique of "sfumato" and the combination of shadows and lights. All these qualities appear together in works such as La Gioconda, The Last Supper and The Virgin of the Rocks.
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In March of 1499, Leonardo works as an architect and military engineer for the Venetians who wanted to build protections in their city.
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Renaissance humanism sees no mutually exclusive polarities between science and the arts.
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Leonardo's scientific method was based fundamentally on observation, science was the captain, the practice was the soldier.
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In 1481 the monastery of San Donato commissioned the Adoration of the Magi, but Leonardo never finished this picture.
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The first work of Leonardo that is known is a part of the Baptism of Christ of Verrocchio and his students. Another painting that seems to date from this period, is The Annunciation.
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The young Leonardo was a lover of nature, who watched with great curiosity. He drew cartoons and practiced specular writing in Tuscan dialect.
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In 1466, when Leonardo began his apprenticeship with Andrea del Verrocchio, the sculptor Donatello, who in turn was Verrocchio's teacher, died.
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April 15, 1452 in Anchiano,Republic of Florence.