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Jedediah Strong Smith is born in Bainbridge, New York.
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Thomas Jefferson is elected as the third president of the United States.
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Thomas Jefferson purchases Louisiana Territory from Napoleon, 800,000 square miles for $15 million.
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The Lewis and Clark expedition sets out from St. Louis.
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At age 13, Jedediah Smith gets a job as a clerk on a Lake Erie commercial vessel.
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Lieut. Oliver Hazzard Perry announces his naval victory at Lake Erie and says, "We have met the enemy and they are ours."
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The American Bible Society is founded.
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Jedediah Smith leaves Lake Erie and moves to St. Louis by himself.
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The Land Act of 1820 reduces the price of land from $1.64 per acre for a minimum of 160 acres to $1.25 an acre for a minimum of 80 acres.
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Benjamin Lundy publishes an early antislavery newspaper, The Genius of Universal Emancipation.
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Stephen F. Austin establishes an American colony in Texas.
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Jedediah Smith joins William Henry Ashley's expedition up the Missouri River.
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Jedediah Smith is mauled and scarred by a grizzly bear near the Black Hills.
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Jedediah Smith discovers the long-lost South Pass, a way to get through the Rocky Mountains to Nevada.
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Thomas Jeffereson and John Adams die on the fiftieth anniversary of the signing of the Declaration of Independence.
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Jedediah Smith arrives at the Mission San Gabriel, where he is kindly welcomed.
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Jedediah Smith and his group of 18 men are attacked by Mohave Indians, killing ten and plundering goods and papers.
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President Jackson signs the Indian Removal Act, which promises financial compensation to Indian tribes that settle West of the Mississippi River.
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Jedediah Smith joins the Santa Fe trade, a group of men who trade fur for goods.
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Jedediah Strong Smith is lanced to death by a group of Comanche Indians near the Cimarron River at the age of 32.
