How transplantation evolved. By Mayo12369 1961 Azathioprine was the first immunosuppression drug made 1966 Antilymphocyte serum was made to help organs like kidneys survive longer. 1990 First successful living donor lung transplant was done. 1999 IOM released organ procurement and transplantation report. 1999 First successful hand transplant was done 2005 First facial transplantation was performed. 2013 First two HIV patients transplant. 2019 First successful bone transplant.