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History of Santana Anna California
Members of the Tongva and Juaneño/Luiseño nations long inhabited the area. The Tongva Indians called the Santa Ana area "Hotuuk."[6] After the 1769 expedition of Gaspar de Portolá out of Mexico City, then capitol of New Spain, Friar Junípero Serra named the area Vallejo de Santa Ana (Valley of Saint Anne, or Santa Ana Valley). On November 1, 1776, Mission San Juan Capistrano was established within this valley. This Santa Ana Valley comprised most of what is now called Orange County.