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A smallpox epidemic begins, and kills thousands of the Native Americans who live in South Dakota.
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The La Vérendrye brothers lead an expedion from Canada to South Dakota.
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Lewis and Clark travel through South Dakota on their way to the Pacific Ocean.
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The Lakota Indians sign a treaty for peace with the government.
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The first permanent town in South Dakota is called Sioux Falls.
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Thousands of homesteaders try to claim land in the Dakota Land Boom.
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South Dakota becomes the 40th state in America.
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The U.S troops kill about 320 Lakotas at the Wounded Knee Massacre.
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The Lakota Tribe is awarded $100 million to make up the loss of their lands, but they don't take it.
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Smoking is banned from all indoor places in South Dakota.