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100,000 deaths
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Brought back by troops from the Middle East; 5 million deaths
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Killed an estimated 100 million, half of the world's known population.
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Killed an estimated 75 to 200 million.
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15 million deaths
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Killed 100,000, a fifth of London's population. 1563, 1592, 1603, and the Great Plague of 1665
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Malaria (no figures on deaths)