History of Plagues

  • 430 BCE

    Plague of Athens

    100,000 deaths
  • 165

    Plague of Antonine

    Brought back by troops from the Middle East; 5 million deaths
  • 541

    Plague of Justinian

    Killed an estimated 100 million, half of the world's known population.
  • Jan 1, 1334

    Black or Bubonic Plague

    Killed an estimated 75 to 200 million.
  • Jan 1, 1545

    Cocoliztli Plague in Mexico

    15 million deaths
  • 1563

    Plagues of London

    Killed 100,000, a fifth of London's population. 1563, 1592, 1603, and the Great Plague of 1665
  • Plague of South America

    Malaria (no figures on deaths)