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when CRISPER was discovered
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Crispr was officially named
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spacer sequences in bacteria and archea were found highly homologous with their viruses
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a genome editing technique CRISPR was developed in vitro
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CRISPR was engineered and used to edit mammalian cells
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Crispr was used to inactivate oncogenic mutations
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Crispr's nuclear dynamics and target recognition were revealed in living cells
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Crispr can target RNA in mammalian cells
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first time Crispr was successfully modified the beta-globin gene mutations in human embryos