History of Hormones

  • Organs influence other body parts

    De Bordeu, Theophile presented the ideal of organs, tissue, and cell discharges influence other body part of the body.
  • Internal secretion

    Bernard, Claude (1813-1878), Claude Bernard invented the term ‘internal secretion’, showing that the body can both break down and build up, complex chemical substances.
  • First isolated hormone

    Adrenaline was the first hormone to be isolated.
  • Isolation of adrenaline in crystalline

    Takamine, Jokichi (1854-1922).Isolation of adrenaline in crystalline form from the adrenal medulla.The blood-pressure-raising principle of the suprarenal glands.
  • New Theory

    Pavlov developed a theory of nerve regulation of salivary and alimentary glands. He included the regulation of the pancreas in his theory.
  • Isolated Secretin

    Ernest Starling and William Bayliss isolated secretin, the first substance to be called a hormone.
  • New Theory

    Bayliss and Starling developed the theory of hormonal control of internal secretion.
  • Adrenal Cortex

    Biedl, Artur (1869-1933), Biedl showed that the adrenal cortex is essential for life. His classic work shows the rapid development of the knowledge of endocrinology.
  • Hormones relieve symtoms

    Kendall, Edward C isolated and crystallized the active principle of the thyroid, named thyroxin. In 1949, he discovered that cortisone could relieve symptoms of rheumatoid arthritis.
  • Endocrine Gland and emotions

    Cannon, Walter Bradford (1871-1945), Cannon showed the close connection between the endocrine glands and the emotions.
  • Human Growth Hormone

    Human growth hormone is discovered by Evans and Long.
  • Insulin

    Banting, Frederick & Mcleod, JJ & Best, Charles, The Canadians Banting, McLeod and Best succeeded in lowering the level of blood-sugar when they used insulin to control the carbohydrate metabolism.
  • Insulin

    Medical student Charles Best, discovered insulin