History of Crime Scene Investigations By kelceyl Mar 1, 1820 The first bullet comparison to catch murder and toxicology which is the examination of blood and tissue May 1, 1840 The development of the first crystal test for Hemoglobin May 1, 1840 The first crystal test for hemoglobin Jun 1, 1860 The first use of photography was brought about. 1880 The development of the first microscope with a comparison bridge