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They used pressing hands of fingers on clay or rocks to investigate fingerprints in prehistoric times.
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In the year 1248 AD the first medical documentation was recorded proving strangulation by drowning.
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During this time, fingerprints and chemicals like poisons were able to be detected at crime scenes.
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Body temperature began to be used to detect the time of death. The portable polygraph machine was invented in 1921.
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Forensic technologies are used in modern investigations. DNA forensics and enhanced bio studies are forms commonly used today.