History of Biochemistry

By Climatechange01
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    Leeuwenhoek

    Observed yeast cells in fermentation sediments
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    Lavoisier

    Sacharose --- (sediment)----> ethanol+CO2
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    Theodor Schawn

    suggested yeast promoted the fermentation process, whose growth was due to sugar consumption and conversion.
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    Louis Pasteur

    He thought it was imposible the fermentation without the simultaneous organization, development and multiplication of the globules or, at least, those present continue to be alive.
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    Eduard Buchner

    Live cells are not essential in the fermentation process
    1897: Beginning of modern biochemistry
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    Wilhelm Kühne

    Coined the term enzyme (in the yeast in greek)
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    Meyerhof

    Principle of universality of the metabolism
    LDH
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    Purification and nature of the enzymes

    1920: Sumner vs Willstäeter
    1930: Sumner and Northrop Nobel Prize 1946
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    High specificity of enzymes

    1936: Keilin and Mann-----> peroxidase
    Chance
    1964: Kunio Yagi------> D-amino acid oxidase
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    Cory and Gerty Theresa

    Isolated F1P and PP in liver
    Nobel Prize 1947
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    Severo Ochoa (Madrid)

    3 ATP/O
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    Lipmann and Hans Krebs

    ATP
    Nobel 1953 shared with Krebs
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    Peter Mitchell

    Chemoosmotic coupling
    Nobel 1978