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Mushrooms were the first-ever hallucinogenic used. This originated from Southeastern Algeria.
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Psilocybin mushrooms were used as a hallucinogenic in a town called Villar del Humo, which is in Spain.
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An Indian named Rig Veda described the use of a psychedelic drink called soma.
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Friar Ramon Pane used psychoactive snuff called cohoba, in what is now the Dominican Republic.
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Richard Spruce observed the Tukano Indians who drank tea as a ritual. He drank a small amount and named it Banisteria Caapi. He then sent samples back home for analysis. This was the first western record of the effects of psychoactive ayahuasca.
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