Genotype Imputation - A Brief Timeline

  • .

  • HapMap Inception

  • Human Genome Project Completed

  • Li and Stephen's Model

    Li and Stephen's Model
  • First GWA study

  • HapMap Phase 1

  • FastPHASE

  • First GWA study to use imputation

  • Imputev1

  • Beagle

  • HapMap Phase II

  • Imputev2

  • HapMap Phase III

  • 1000 Genomes Pilot

  • MaCH

  • Pre-Phasing

  • 1000 Genomes Phase 1

  • Minimac

  • Minimac2

  • 1000 Genomes Phase 3

  • Michigan Imputation Server

  • Minimac3

  • Beagle4.1

  • Haplotype Reference Consortium

  • TOPMed

  • Minimac4

  • MetaMinimac