Genotype Imputation - A Brief Timeline By facebooker_1491200784251589 2001 . 2002 HapMap Inception 2003 Human Genome Project Completed 2003 Li and Stephen's Model 2005 First GWA study 2005 HapMap Phase 1 2006 FastPHASE 2007 First GWA study to use imputation 2007 Imputev1 2007 Beagle 2007 HapMap Phase II 2009 Imputev2 2010 HapMap Phase III 2010 1000 Genomes Pilot 2010 MaCH 2012 Pre-Phasing 2012 1000 Genomes Phase 1 2012 Minimac 2014 Minimac2 2014 1000 Genomes Phase 3 2015 Michigan Imputation Server 2015 Minimac3 2015 Beagle4.1 2016 Haplotype Reference Consortium 2017 TOPMed 2017 Minimac4 2017 MetaMinimac